A Nut for Every Bolt: Subunit-Selective Inhibitors of the Immunoproteasome and Their Therapeutic Potential

At the heart of the ubiquitin–proteasome system, the 20S proteasome core particle (CP) breaks down the majority of intracellular proteins tagged for destruction. Thereby, the CP controls many cellular processes including cell cycle progression and cell signalling. Inhibitors of the CP can suppress t...

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Detalles Bibliográficos
Autores principales: Huber, Eva M., Groll, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394499/
https://www.ncbi.nlm.nih.gov/pubmed/34440698
http://dx.doi.org/10.3390/cells10081929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394499/
https://www.ncbi.nlm.nih.gov/pubmed/34440698
http://dx.doi.org/10.3390/cells10081929

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