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Loosening ER–Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain
Presenilin 2 (PS2), one of the three proteins in which mutations are linked to familial Alzheimer’s disease (FAD), exerts different functions within the cell independently of being part of the γ-secretase complex, thus unrelated to toxic amyloid peptide formation. In particular, its enrichment in en...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394530/ https://www.ncbi.nlm.nih.gov/pubmed/34440738 http://dx.doi.org/10.3390/cells10081968 |