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Loosening ER–Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain

Presenilin 2 (PS2), one of the three proteins in which mutations are linked to familial Alzheimer’s disease (FAD), exerts different functions within the cell independently of being part of the γ-secretase complex, thus unrelated to toxic amyloid peptide formation. In particular, its enrichment in en...

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Detalles Bibliográficos
Autores principales: Rossini, Michela, García-Casas, Paloma, Filadi, Riccardo, Pizzo, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394530/
https://www.ncbi.nlm.nih.gov/pubmed/34440738
http://dx.doi.org/10.3390/cells10081968

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