Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

BACKGROUND: Sleep-disordered breathing is a common disorder associated with significant morbidity. The genetic architecture of sleep-disordered breathing remains poorly understood. Through the NHLBI Trans-Omics for Precision Medicine (TOPMed) program, we performed the first whole-genome sequence ana...

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Detalles Bibliográficos
Autores principales: Cade, Brian E., Lee, Jiwon, Sofer, Tamar, Wang, Heming, Zhang, Man, Chen, Han, Gharib, Sina A., Gottlieb, Daniel J., Guo, Xiuqing, Lane, Jacqueline M., Liang, Jingjing, Lin, Xihong, Mei, Hao, Patel, Sanjay R., Purcell, Shaun M., Saxena, Richa, Shah, Neomi A., Evans, Daniel S., Hanis, Craig L., Hillman, David R., Mukherjee, Sutapa, Palmer, Lyle J., Stone, Katie L., Tranah, Gregory J., Abecasis, Gonçalo R., Boerwinkle, Eric A., Correa, Adolfo, Cupples, L. Adrienne, Kaplan, Robert C., Nickerson, Deborah A., North, Kari E., Psaty, Bruce M., Rotter, Jerome I., Rich, Stephen S., Tracy, Russell P., Vasan, Ramachandran S., Wilson, James G., Zhu, Xiaofeng, Redline, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394596/
https://www.ncbi.nlm.nih.gov/pubmed/34446064
http://dx.doi.org/10.1186/s13073-021-00917-8

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