Cargando…

Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis

Tubulin post-translational modifications regulate microtubule properties and functions. Mitotic spindle microtubules are highly modified. While tubulin detyrosination promotes proper mitotic progression by recruiting specific microtubule-associated proteins motors, tubulin acetylation that occurs on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rasamizafy, Sylvia Fenosoa, Delsert, Claude, Rabeharivelo, Gabriel, Cau, Julien, Morin, Nathalie, van Dijk, Juliette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394630/ https://www.ncbi.nlm.nih.gov/pubmed/34440628 http://dx.doi.org/10.3390/cells10081859

Ejemplares similares

PAK1 Regulates MEC-17 Acetyltransferase Activity and Microtubule Acetylation during Proplatelet Extension
por: van Dijk, Juliette, et al.
Publicado: (2020)

Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation
por: van Dijk, Juliette, et al.
Publicado: (2018)

Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis
por: Bompard, Guillaume, et al.
Publicado: (2010)

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly
por: Ohta, Shinya, et al.
Publicado: (2015)

A novel p21-activated kinase binds the actin and microtubule networks and induces microtubule stabilization
por: Cau, Julien, et al.
Publicado: (2001)

MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1
por: Zhao, Wei, et al.
Publicado: (2016)

Synergy between Multiple Microtubule-Generating Pathways Confers Robustness to Centrosome-Driven Mitotic Spindle Formation
por: Hayward, Daniel, et al.
Publicado: (2014)

The sequential activation of the mitotic microtubule assembly pathways favors bipolar spindle formation
por: Cavazza, Tommaso, et al.
Publicado: (2016)

Centrosome–nuclear axis repositioning drives the assembly of a bipolar spindle scaffold to ensure mitotic fidelity
por: Nunes, Vanessa, et al.
Publicado: (2020)

Chromosome misalignment is associated with PLK1 activity at cenexin-positive mitotic centrosomes
por: Colicino, Erica G., et al.
Publicado: (2019)

SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression
por: Yuki, Ryuzaburo, et al.
Publicado: (2023)

Sinup is essential for the integrity of centrosomes and mitotic spindles in zebrafish embryos
por: Yoo, Kyeong-Won, et al.
Publicado: (2017)

Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1
por: Mbom, Bertrade C., et al.
Publicado: (2014)

Spatial and Temporal Scaling of Microtubules and Mitotic Spindles
por: Lacroix, Benjamin, et al.
Publicado: (2022)

Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans
por: O'Toole, Eileen T., et al.
Publicado: (2003)

Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly
por: Asteriti, Italia Anna, et al.
Publicado: (2015)

PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
por: Mollinari, Cristiana, et al.
Publicado: (2002)

CDK11(p58) Is Required for Centriole Duplication and Plk4 Recruitment to Mitotic Centrosomes
por: Franck, Nathalie, et al.
Publicado: (2011)

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization
por: Fielding, Andrew B., et al.
Publicado: (2008)

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes
por: Gaglio, Tirso, et al.
Publicado: (1997)

The Bipolar Kinesin, KLP61F, Cross-links Microtubules within Interpolar Microtubule Bundles of Drosophila Embryonic Mitotic Spindles
por: Sharp, David J., et al.
Publicado: (1999)

Pathogenic BRCA1 variants disrupt PLK1-regulation of mitotic spindle orientation
por: He, Zhengcheng, et al.
Publicado: (2022)

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation
por: Faienza, Fiorella, et al.
Publicado: (2023)

Plk1-Dependent Recruitment of γ-Tubulin Complexes to Mitotic Centrosomes Involves Multiple PCM Components
por: Haren, Laurence, et al.
Publicado: (2009)

Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes
por: Platani, Melpomeni, et al.
Publicado: (2015)

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
por: Wong, Siu‐Shing, et al.
Publicado: (2022)

Poleward microtubule flux mitotic spindles assembled in vitro
Publicado: (1991)

Microtubule pivoting enables mitotic spindle assembly in S. cerevisiae
por: Fong, Kimberly K., et al.
Publicado: (2021)

KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number
por: Fournier, Marjorie, et al.
Publicado: (2016)

Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression
por: Plessner, Matthias, et al.
Publicado: (2019)

MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression
por: Zhu, Mei, et al.
Publicado: (2013)

Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes
por: Zhu, Zihan, et al.
Publicado: (2023)

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo
Publicado: (1989)

The mitotic spindle is chiral due to torques within microtubule bundles
por: Novak, Maja, et al.
Publicado: (2018)

Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly
por: Toso, Alberto, et al.
Publicado: (2009)

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
por: Sánchez-Huertas, Carlos, et al.
Publicado: (2016)

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
por: Goshima, Gohta, et al.
Publicado: (2008)

Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis
por: Reverte, Carlos G., et al.
Publicado: (2006)

Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization
por: Heald, Rebecca, et al.
Publicado: (1997)

Centrophilin: a novel mitotic spindle protein involved in microtubule nucleation
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_2n5748que1kh5qtlln5fb1782m