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Effects of Mild Excitotoxic Stimulus on Mitochondria Ca(2+) Handling in Hippocampal Cultures of a Mouse Model of Alzheimer’s Disease

In Alzheimer’s disease (AD), the molecular mechanisms involved in the neurodegeneration are still incompletely defined, though this aspect is crucial for a better understanding of the malady and for devising effective therapies. Mitochondrial dysfunctions and altered Ca(2+) signaling have long been...

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Detalles Bibliográficos
Autores principales: Rigotto, Giulia, Zentilin, Lorena, Pozzan, Tullio, Basso, Emy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394681/
https://www.ncbi.nlm.nih.gov/pubmed/34440815
http://dx.doi.org/10.3390/cells10082046