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Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394746/ https://www.ncbi.nlm.nih.gov/pubmed/34439786 http://dx.doi.org/10.3390/biom11081120 |
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author | Bakare, Olalekan Olanrewaju Gokul, Arun Wu, Ruomou Niekerk, Lee-Ann Klein, Ashwil Keyster, Marshall |
author_facet | Bakare, Olalekan Olanrewaju Gokul, Arun Wu, Ruomou Niekerk, Lee-Ann Klein, Ashwil Keyster, Marshall |
author_sort | Bakare, Olalekan Olanrewaju |
collection | PubMed |
description | The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates due to several compensatory advantages over the non-specificity of the current treatment regimens. This review aimed to highlight the ravaging incidence of cancer, the use of ACPs in cancer treatment with their mechanisms, ACP discovery and delivery methods, and the limitations for their use. This would create awareness for identifying more ACPs with better specificity, accuracy and sensitivity towards the disease. It would also promote their efficacious utilization in biotechnology, medical sciences and molecular biology to ease the severity of the disease and enable the patients living with these conditions to develop an accommodating lifestyle. |
format | Online Article Text |
id | pubmed-8394746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83947462021-08-28 Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer Bakare, Olalekan Olanrewaju Gokul, Arun Wu, Ruomou Niekerk, Lee-Ann Klein, Ashwil Keyster, Marshall Biomolecules Review The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host defense peptides, also known as antimicrobial peptides, which have emerged as therapeutic and diagnostic candidates due to several compensatory advantages over the non-specificity of the current treatment regimens. This review aimed to highlight the ravaging incidence of cancer, the use of ACPs in cancer treatment with their mechanisms, ACP discovery and delivery methods, and the limitations for their use. This would create awareness for identifying more ACPs with better specificity, accuracy and sensitivity towards the disease. It would also promote their efficacious utilization in biotechnology, medical sciences and molecular biology to ease the severity of the disease and enable the patients living with these conditions to develop an accommodating lifestyle. MDPI 2021-07-29 /pmc/articles/PMC8394746/ /pubmed/34439786 http://dx.doi.org/10.3390/biom11081120 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bakare, Olalekan Olanrewaju Gokul, Arun Wu, Ruomou Niekerk, Lee-Ann Klein, Ashwil Keyster, Marshall Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title | Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title_full | Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title_fullStr | Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title_full_unstemmed | Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title_short | Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer |
title_sort | biomedical relevance of novel anticancer peptides in the sensitive treatment of cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394746/ https://www.ncbi.nlm.nih.gov/pubmed/34439786 http://dx.doi.org/10.3390/biom11081120 |
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