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Pan-Cancer Analysis of Immune Complement Signature C3/C5/C3AR1/C5AR1 in Association with Tumor Immune Evasion and Therapy Resistance

SIMPLE SUMMARY: We used multi-omics approaches to evaluate the association of complement signature C3/C5/C3AR1/C5AR1 with tumor immune phenotypes and prognosis across various cancer types. We found that the gene signatures have deregulated expression in human malignancies and demonstrated context-de...

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Detalles Bibliográficos
Autores principales: Lawal, Bashir, Tseng, Sung-Hui, Olugbodi, Janet Olayemi, Iamsaard, Sitthichai, Ilesanmi, Omotayo B., Mahmoud, Mohamed H., Ahmed, Sahar H., Batiha, Gaber El-Saber, Wu, Alexander T. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394789/
https://www.ncbi.nlm.nih.gov/pubmed/34439277
http://dx.doi.org/10.3390/cancers13164124