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Microdissected Tissue vs. Tissue Slices—A Comparative Study of Tumor Explant Models Cultured On-Chip and Off-Chip

SIMPLE SUMMARY: Cancer drugs have the lowest success rate of approval in drug development programs. In order to address this, predictive preclinical assays that correctly reflect the clinical efficacy of a drug represent an urgent need in both clinical oncology and pharmaceutical research. To addres...

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Detalles Bibliográficos
Autores principales: Dorrigiv, Dina, Simeone, Kayla, Communal, Laudine, Kendall-Dupont, Jennifer, St-Georges-Robillard, Amélie, Péant, Benjamin, Carmona, Euridice, Mes-Masson, Anne-Marie, Gervais, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394960/
https://www.ncbi.nlm.nih.gov/pubmed/34439362
http://dx.doi.org/10.3390/cancers13164208

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