Cargando…

Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations

The purpose of this study was to prepare poly (D-L) lactide-co-glycolide (PLGA) and poly ε-caprolactone (PCL) nanofibers containing metronidazole and amoxicillin using an electrospinning process as intrapocket sustained-release drug delivery systems for the treatment of periodontal diseases. Scannin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mirzaeei, Shahla, Mansurian, Mahla, Asare-Addo, Kofi, Nokhodchi, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395018/ https://www.ncbi.nlm.nih.gov/pubmed/34440179 http://dx.doi.org/10.3390/biomedicines9080975

Ejemplares similares

Polyvinyl Alcohol/Chitosan Single-Layered and Polyvinyl Alcohol/Chitosan/Eudragit RL100 Multi-layered Electrospun Nanofibers as an Ocular Matrix for the Controlled Release of Ofloxacin: an In Vitro and In Vivo Evaluation
por: Mirzaeei, Shahla, et al.
Publicado: (2021)

The effect of metronidazole plus amoxicillin or metronidazole plus penicillin V on periodontal pathogens in an in vitro biofilm model
por: Dabija‐Wolter, Gabriela, et al.
Publicado: (2018)

Eudragit(®) L100/Polyvinyl Alcohol Nanoparticles Impregnated Mucoadhesive Films as Ocular Inserts for Controlled Delivery of Erythromycin: Development, Characterization and In Vivo Evaluation
por: Mirzaeei, Shahla, et al.
Publicado: (2022)

The effect of metronidazole plus amoxicillin or metronidazole plus penicillin V on a periodontal biofilm model. An in vitro study.
por: Al-Zubaydi, Sundus Saad, et al.
Publicado: (2017)

Metronidazole and amoxicillin association in aggressive periodontitis: A systematic review and meta-analysis
por: Mendes, Cácio Lopes, et al.
Publicado: (2020)

Polymeric Inserts Containing Eudragit(®) L100 Nanoparticle for Improved Ocular Delivery of Azithromycin
por: Taghe, Shiva, et al.
Publicado: (2020)

Evaluation of Electrospun PCL-PLGA for Sustained Delivery of Kartogenin
por: Elder, Steven, et al.
Publicado: (2022)

The preosteoblast response of electrospinning PLGA/PCL nanofibers: effects of biomimetic architecture and collagen I
por: Qian, Yunzhu, et al.
Publicado: (2016)

Chlorhexidine, clotrimazole, metronidazole and combination therapy in the treatment of vaginal infections
por: Mirzaeei, Shahla, et al.
Publicado: (2021)

Non-Surgical Periodontal Therapy with Adjunctive Amoxicillin/Metronidazole or Metronidazole When No Aggregatibacter actinomycetemcomitans Is Detected—A Randomized Clinical Trial
por: Jentsch, Holger F. R., et al.
Publicado: (2020)

Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical treatment in generalized aggressive periodontitis
por: Guzeldemir-Akcakanat, Esra, et al.
Publicado: (2015)

Lectin Protein as a Promising Component to Functionalize Micelles, Liposomes and Lipid NPs against Coronavirus
por: Alavi, Mehran, et al.
Publicado: (2020)

Rapid releasing naproxen Liqui-Pellet using effervescent agent and neusilin US2
por: Lam, Matthew, et al.
Publicado: (2021)

Liqui-Tablet: the Innovative Oral Dosage Form Using the Newly Developed Liqui-Mass Technology
por: Lam, Matthew, et al.
Publicado: (2021)

Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery
por: Abid, Zarmeena, et al.
Publicado: (2019)

Evaluation of metronidazole nanofibers in patients with chronic periodontitis: A clinical study
por: Chaturvedi, Thakur Prasad, et al.
Publicado: (2012)

Preparation of Azithromycin Nanofibers as Controlled Release Ophthalmic Drug Carriers Using Electrospinning Technique: In Vitro and In Vivo Characterization
por: Taghe, Shiva, et al.
Publicado: (2022)

Amoxicillin/metronidazole: Toxic epidermal necrolysis: case report
Publicado: (2021)

Physical PEGylation Enhances The Cytotoxicity Of 5-Fluorouracil-Loaded PLGA And PCL Nanoparticles
por: Ashour, Abdelkader E, et al.
Publicado: (2019)

Efficacy of Systemic Amoxicillin–Metronidazole in Periodontitis Patients with Diabetes Mellitus: A Systematic Review of Randomized Clinical Trials
por: Mugri, Maryam Hassan
Publicado: (2022)

Preparation and Evaluation of Eudragit® L100 Nanoparticles Loaded Impregnated with KT Tromethamine Loaded PVA -HEC Insertions for Ophthalmic Drug Delivery
por: Mohammadi, Ghobad, et al.
Publicado: (2019)

Design and Development of Antibacterial/Anti-inflammatory Dual Drug-Loaded Nanofibrous Inserts for Ophthalmic Sustained Delivery of Gentamicin and Methylprednisolone: In Vitro Bioassay, Solvent, and Method Effects’ Evaluation
por: Mirzaeei, Shahla, et al.
Publicado: (2022)

A novel drug delivery system using acyclovir nanofiber patch for topical treatment of recurrent herpes labialis: A randomized clinical trial
por: Golestannejad, Zahra, et al.
Publicado: (2021)

The concomitant administration of systemic amoxicillin and metronidazole compared to scaling and root planing alone in treating periodontitis: =a systematic review=
por: Zandbergen, Dina, et al.
Publicado: (2016)

Impact of metronidazole and amoxicillin combination on matrix metalloproteinases-1 and tissue inhibitors of matrix metalloproteinases balance in generalized aggressive periodontitis
por: Cifcibasi, Emine, et al.
Publicado: (2015)

The ideal time of systemic metronidazole and amoxicillin administration in the treatment of severe periodontitis: study protocol for a randomized controlled trial
por: Feres, Magda, et al.
Publicado: (2018)

Preparation and modeling of three‐layered PCL/PLGA/PCL fibrous scaffolds for prolonged drug release
por: Milosevic, Miljan, et al.
Publicado: (2020)

Clinical benefits of systemic amoxicillin/metronidazole may depend on periodontitis severity and patients' age: An exploratory sub‐analysis of the ABPARO trial
por: Eickholz, Peter, et al.
Publicado: (2019)

A multilevel analysis of a randomized clinical trial comparing adjunctive moxifloxacin versus amoxicillin/metronidazole for the treatment of aggressive periodontitis
por: Ardila, Carlos-Martín, et al.
Publicado: (2021)

Targeted drug-loaded PLGA-PCL microspheres for specific and localized treatment of triple negative breast cancer
por: Nwazojie, Chukwudalu C., et al.
Publicado: (2023)

Significant Short-Term Shifts in the Microbiomes of Smokers With Periodontitis After Periodontal Therapy With Amoxicillin & Metronidazole as Revealed by 16S rDNA Amplicon Next Generation Sequencing
por: Hagenfeld, Daniel, et al.
Publicado: (2020)

Dry Powder Formulation of Simvastatin Nanoparticles for Potential Application in Pulmonary Arterial Hypertension
por: Zendehdel Baher, Shalaleh, et al.
Publicado: (2022)

Preparation and Characterization of Simvastatin-Loaded PCL/PEG Nanofiber Membranes for Drug Sustained Release
por: Pan, Lu, et al.
Publicado: (2022)

Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran
por: Khademi, Farzad, et al.
Publicado: (2013)

Author Correction: Preparation and modeling of three‐layered PCL/PLGA/PCL fibrous scaffolds for prolonged drug release
por: Milosevic, Miljan, et al.
Publicado: (2021)

Design of Novel Nanoemulsion Formulations for Topical Ocular Delivery of Itraconazole: Development, Characterization and In Vitro Bioassay
por: Mehrandish, Saba, et al.
Publicado: (2022)

Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line Helicobacter pylori eradication therapy
por: Nishizawa, Toshihiro, et al.
Publicado: (2012)

Comparison of the efficacy of amoxicillin-clavulanic acid with metronidazole to azithromycin with metronidazole after surgical removal of impacted lower third molar to prevent infection
por: Sayd, Shermil, et al.
Publicado: (2018)

Efficacy of clindamycin compared with amoxicillin-metronidazole after a 7-day regimen in the treatment of periodontitis in patients with diabetes: a randomized clinical trial
por: Gómez-Sandoval, Juan Ramón, et al.
Publicado: (2020)

Comparing the Antimicrobial In Vitro Efficacy of Amoxicillin/Metronidazole against Azithromycin—A Systematic Review
por: Kaufmann, Manuela, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3qr1rm5b3r9gs2rqt042f1hpk1