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Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults

Postprandial lipemia, glycemia and oxidative stress may affect the occurrence of cardiovascular disease. The purpose of the present intervention study was to investigate the effect of a spread cheese enriched with mountain tea (Sideritis sp.) and orange peel (Citrus sinensis) extract on postprandial...

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Autores principales: Papagianni, Olga, Argyri, Konstantina, Loukas, Thomas, Magkoutis, Athanasios, Biagki, Theodora, Skalkos, Dimitrios, Kafetzopoulos, Dimitrios, Dimou, Charalampia, Karantonis, Haralampos C., Koutelidakis, Antonios E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395019/
https://www.ncbi.nlm.nih.gov/pubmed/34439907
http://dx.doi.org/10.3390/biom11081241
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author Papagianni, Olga
Argyri, Konstantina
Loukas, Thomas
Magkoutis, Athanasios
Biagki, Theodora
Skalkos, Dimitrios
Kafetzopoulos, Dimitrios
Dimou, Charalampia
Karantonis, Haralampos C.
Koutelidakis, Antonios E.
author_facet Papagianni, Olga
Argyri, Konstantina
Loukas, Thomas
Magkoutis, Athanasios
Biagki, Theodora
Skalkos, Dimitrios
Kafetzopoulos, Dimitrios
Dimou, Charalampia
Karantonis, Haralampos C.
Koutelidakis, Antonios E.
author_sort Papagianni, Olga
collection PubMed
description Postprandial lipemia, glycemia and oxidative stress may affect the occurrence of cardiovascular disease. The purpose of the present intervention study was to investigate the effect of a spread cheese enriched with mountain tea (Sideritis sp.) and orange peel (Citrus sinensis) extract on postprandial metabolic biomarkers in healthy volunteers. In a cross-over design, 14 healthy subjects 20–30 years old were consumed either a meal rich in fat and carbohydrates (80 g white bread, 40 g butter and 30 g full fat spread cheese) or a meal with the spread cheese enriched with 6% mountain tea–orange peel extract. Differences in postprandial total plasma antioxidant capacity, resistance of plasma to oxidation, serum lipids, glucose and uric acid levels were evaluated at 0, 1.5 and 3 h after consumption. Plasma total antioxidant capacity was significantly increased 3 h after the consumption of the meal in the presence of the extract-enriched cheese, compared to the conventional cheese (p = 0.05). Plasma resistance to oxidation was increased at 30 min in the Functional meal compared with the Control meal. A tendency to decrease the postprandial rise in glucose and triglyceride levels, 1.5 h and 3 h, respectively, after the intake of the meal with the extract-enriched cheese was observed (p = 0.062). No significant changes in the concentrations of the remaining biomarkers studied were observed (p > 0.05). Further studies with a larger sample are needed in both healthy adults and patients with cardiovascular disease to draw safer conclusions about the postprandial effect of the extracts on metabolic biomarkers that predict cardiovascular risk.
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spelling pubmed-83950192021-08-28 Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults Papagianni, Olga Argyri, Konstantina Loukas, Thomas Magkoutis, Athanasios Biagki, Theodora Skalkos, Dimitrios Kafetzopoulos, Dimitrios Dimou, Charalampia Karantonis, Haralampos C. Koutelidakis, Antonios E. Biomolecules Article Postprandial lipemia, glycemia and oxidative stress may affect the occurrence of cardiovascular disease. The purpose of the present intervention study was to investigate the effect of a spread cheese enriched with mountain tea (Sideritis sp.) and orange peel (Citrus sinensis) extract on postprandial metabolic biomarkers in healthy volunteers. In a cross-over design, 14 healthy subjects 20–30 years old were consumed either a meal rich in fat and carbohydrates (80 g white bread, 40 g butter and 30 g full fat spread cheese) or a meal with the spread cheese enriched with 6% mountain tea–orange peel extract. Differences in postprandial total plasma antioxidant capacity, resistance of plasma to oxidation, serum lipids, glucose and uric acid levels were evaluated at 0, 1.5 and 3 h after consumption. Plasma total antioxidant capacity was significantly increased 3 h after the consumption of the meal in the presence of the extract-enriched cheese, compared to the conventional cheese (p = 0.05). Plasma resistance to oxidation was increased at 30 min in the Functional meal compared with the Control meal. A tendency to decrease the postprandial rise in glucose and triglyceride levels, 1.5 h and 3 h, respectively, after the intake of the meal with the extract-enriched cheese was observed (p = 0.062). No significant changes in the concentrations of the remaining biomarkers studied were observed (p > 0.05). Further studies with a larger sample are needed in both healthy adults and patients with cardiovascular disease to draw safer conclusions about the postprandial effect of the extracts on metabolic biomarkers that predict cardiovascular risk. MDPI 2021-08-19 /pmc/articles/PMC8395019/ /pubmed/34439907 http://dx.doi.org/10.3390/biom11081241 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Papagianni, Olga
Argyri, Konstantina
Loukas, Thomas
Magkoutis, Athanasios
Biagki, Theodora
Skalkos, Dimitrios
Kafetzopoulos, Dimitrios
Dimou, Charalampia
Karantonis, Haralampos C.
Koutelidakis, Antonios E.
Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title_full Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title_fullStr Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title_full_unstemmed Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title_short Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults
title_sort postprandial bioactivity of a spread cheese enriched with mountain tea and orange peel extract in plasma oxidative stress status, serum lipids and glucose levels: an interventional study in healthy adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395019/
https://www.ncbi.nlm.nih.gov/pubmed/34439907
http://dx.doi.org/10.3390/biom11081241
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