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An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study

Automated artificial intelligence (AI) systems enable the integration of different types of data from various sources for clinical decision-making. The aim of this study is to propose a pipeline to develop a fully automated clinician-friendly AI-enabled database platform for breast cancer survival p...

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Autores principales: Ganggayah, Mogana Darshini, Dhillon, Sarinder Kaur, Islam, Tania, Kalhor, Foad, Chiang, Teh Chean, Kalafi, Elham Yousef, Taib, Nur Aishah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395030/
https://www.ncbi.nlm.nih.gov/pubmed/34441426
http://dx.doi.org/10.3390/diagnostics11081492
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author Ganggayah, Mogana Darshini
Dhillon, Sarinder Kaur
Islam, Tania
Kalhor, Foad
Chiang, Teh Chean
Kalafi, Elham Yousef
Taib, Nur Aishah
author_facet Ganggayah, Mogana Darshini
Dhillon, Sarinder Kaur
Islam, Tania
Kalhor, Foad
Chiang, Teh Chean
Kalafi, Elham Yousef
Taib, Nur Aishah
author_sort Ganggayah, Mogana Darshini
collection PubMed
description Automated artificial intelligence (AI) systems enable the integration of different types of data from various sources for clinical decision-making. The aim of this study is to propose a pipeline to develop a fully automated clinician-friendly AI-enabled database platform for breast cancer survival prediction. A case study of breast cancer survival cohort from the University Malaya Medical Centre was used to develop and evaluate the pipeline. A relational database and a fully automated system were developed by integrating the database with analytical modules (machine learning, automated scoring for quality of life, and interactive visualization). The developed pipeline, iSurvive has helped in enhancing data management as well as to visualize important prognostic variables and survival rates. The embedded automated scoring module demonstrated quality of life of patients whereas the interactive visualizations could be used by clinicians to facilitate communication with patients. The pipeline proposed in this study is a one-stop center to manage data, to automate analytics using machine learning, to automate scoring and to produce explainable interactive visuals to enhance clinician-patient communication along the survivorship period to modify behaviours that relate to prognosis. The pipeline proposed can be modelled on any disease not limited to breast cancer.
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spelling pubmed-83950302021-08-28 An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study Ganggayah, Mogana Darshini Dhillon, Sarinder Kaur Islam, Tania Kalhor, Foad Chiang, Teh Chean Kalafi, Elham Yousef Taib, Nur Aishah Diagnostics (Basel) Article Automated artificial intelligence (AI) systems enable the integration of different types of data from various sources for clinical decision-making. The aim of this study is to propose a pipeline to develop a fully automated clinician-friendly AI-enabled database platform for breast cancer survival prediction. A case study of breast cancer survival cohort from the University Malaya Medical Centre was used to develop and evaluate the pipeline. A relational database and a fully automated system were developed by integrating the database with analytical modules (machine learning, automated scoring for quality of life, and interactive visualization). The developed pipeline, iSurvive has helped in enhancing data management as well as to visualize important prognostic variables and survival rates. The embedded automated scoring module demonstrated quality of life of patients whereas the interactive visualizations could be used by clinicians to facilitate communication with patients. The pipeline proposed in this study is a one-stop center to manage data, to automate analytics using machine learning, to automate scoring and to produce explainable interactive visuals to enhance clinician-patient communication along the survivorship period to modify behaviours that relate to prognosis. The pipeline proposed can be modelled on any disease not limited to breast cancer. MDPI 2021-08-18 /pmc/articles/PMC8395030/ /pubmed/34441426 http://dx.doi.org/10.3390/diagnostics11081492 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ganggayah, Mogana Darshini
Dhillon, Sarinder Kaur
Islam, Tania
Kalhor, Foad
Chiang, Teh Chean
Kalafi, Elham Yousef
Taib, Nur Aishah
An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title_full An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title_fullStr An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title_full_unstemmed An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title_short An Artificial Intelligence-Enabled Pipeline for Medical Domain: Malaysian Breast Cancer Survivorship Cohort as a Case Study
title_sort artificial intelligence-enabled pipeline for medical domain: malaysian breast cancer survivorship cohort as a case study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395030/
https://www.ncbi.nlm.nih.gov/pubmed/34441426
http://dx.doi.org/10.3390/diagnostics11081492
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