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Ageing Causes Ultrastructural Modification to Calcium Release Units and Mitochondria in Cardiomyocytes
Ageing is associated with an increase in the incidence of heart failure, even if the existence of a real age-related cardiomyopathy remains controversial. Effective contraction and relaxation of cardiomyocytes depend on efficient production of ATP (handled by mitochondria) and on proper Ca(2+) suppl...
Autores principales: | Di Fonso, Alessia, Pietrangelo, Laura, D’Onofrio, Laura, Michelucci, Antonio, Boncompagni, Simona, Protasi, Feliciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395047/ https://www.ncbi.nlm.nih.gov/pubmed/34445071 http://dx.doi.org/10.3390/ijms22168364 |
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