Cargando…
WNT Signaling as a Therapeutic Target for Glioblastoma
The WNT (Wingless/Integrated) signaling pathway is implicated in various stages of glioblastoma, which is an aggressive brain tumor for which therapeutic options are limited. WNT has been recognized as a hallmark of therapeutic challenge due to its context-dependent role and critical function in hea...
Autores principales: | Latour, Michael, Her, Nam-Gu, Kesari, Santosh, Nurmemmedov, Elmar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395085/ https://www.ncbi.nlm.nih.gov/pubmed/34445128 http://dx.doi.org/10.3390/ijms22168428 |
Ejemplares similares
-
Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer
por: Cheltsov, Anton, et al.
Publicado: (2020) -
Glioblastoma stem cells and Wnt signaling pathway: molecular mechanisms and therapeutic targets
por: Guan, Ruoyu, et al.
Publicado: (2020) -
Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis
por: Kim, Myoung Sook, et al.
Publicado: (2020) -
A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma
por: Yenugonda, Venkata, et al.
Publicado: (2017) -
Multiple spatially related pharmacophores define small molecule inhibitors of OLIG2 in glioblastoma
por: Tsigelny, Igor F., et al.
Publicado: (2015)