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Severe COVID-19 Patients Show an Increase in Soluble TNFR1 and ADAM17, with a Relationship to Mortality

Overproduction of inflammatory cytokines is a keystone event in COVID-19 pathogenesis; TNF and its receptors (TNFR1 and TNFR2) are critical pro-inflammatory molecules. ADAM17 releases the soluble (sol) forms of TNF, TNFR1, and TNFR2. This study evaluated TNF, TNFRs, and ADAM17 at the protein, transc...

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Detalles Bibliográficos
Autores principales:	Palacios, Yadira, Ruiz, Andy, Ramón-Luing, Lucero A., Ocaña-Guzman, Ranferi, Barreto-Rodriguez, Omar, Sánchez-Monciváis, Anahí, Tecuatzi-Cadena, Brenda, Regalado-García, Ana G., Pineda-Gudiño, Rey David, García-Martínez, Alicia, Juárez-Hernández, Fortunato, Farias-Contreras, Juan Pablo, Fricke-Galindo, Ingrid, Pérez-Rubio, Gloria, Falfán-Valencia, Ramcés, Buendia-Roldan, Ivette, Medina-Quero, Karen, Chavez-Galan, Leslie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395100/ https://www.ncbi.nlm.nih.gov/pubmed/34445140 http://dx.doi.org/10.3390/ijms22168423

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