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Nitric Oxide-Releasing Drug Glyceryl Trinitrate Targets JAK2/STAT3 Signaling, Migration and Invasion of Triple-Negative Breast Cancer Cells
Triple-negative breast cancer (TNBC) is a highly aggressive disease with invasive and metastasizing properties associated with a poor prognosis. The STAT3 signaling pathway has shown a pivotal role in cancer cell migration, invasion, metastasis and drug resistance of TNBC cells. IL-6 is a main upstr...
Autores principales: | Bouaouiche, Sarra, Ghione, Silvia, Sghaier, Randa, Burgy, Olivier, Racoeur, Cindy, Derangère, Valentin, Bettaieb, Ali, Plenchette, Stéphanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395103/ https://www.ncbi.nlm.nih.gov/pubmed/34445170 http://dx.doi.org/10.3390/ijms22168449 |
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