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An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies

Developmental and epileptic encephalopathies (DEEs) are complex conditions characterized primarily by seizures associated with neurodevelopmental and motor deficits. Recent evidence supports sigma-1 receptor modulation in both neuroprotection and antiseizure activity, suggesting that sigma-1 recepto...

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Detalles Bibliográficos
Autores principales: Martin, Parthena, Reeder, Thadd, Sourbron, Jo, de Witte, Peter A. M., Gammaitoni, Arnold R., Galer, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395113/
https://www.ncbi.nlm.nih.gov/pubmed/34445144
http://dx.doi.org/10.3390/ijms22168416