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An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies
Developmental and epileptic encephalopathies (DEEs) are complex conditions characterized primarily by seizures associated with neurodevelopmental and motor deficits. Recent evidence supports sigma-1 receptor modulation in both neuroprotection and antiseizure activity, suggesting that sigma-1 recepto...
Autores principales: | Martin, Parthena, Reeder, Thadd, Sourbron, Jo, de Witte, Peter A. M., Gammaitoni, Arnold R., Galer, Bradley S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395113/ https://www.ncbi.nlm.nih.gov/pubmed/34445144 http://dx.doi.org/10.3390/ijms22168416 |
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