The Role of lncRNA in the Development of Tumors, including Breast Cancer

Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules se...

Descripción completa

Detalles Bibliográficos
Autores principales: Smolarz, Beata, Zadrożna-Nowak, Anna, Romanowicz, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395147/
https://www.ncbi.nlm.nih.gov/pubmed/34445129
http://dx.doi.org/10.3390/ijms22168427
_version_ 1783744106913071104
author Smolarz, Beata
Zadrożna-Nowak, Anna
Romanowicz, Hanna
author_facet Smolarz, Beata
Zadrożna-Nowak, Anna
Romanowicz, Hanna
author_sort Smolarz, Beata
collection PubMed
description Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma.
format Online
Article
Text
id pubmed-8395147
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83951472021-08-28 The Role of lncRNA in the Development of Tumors, including Breast Cancer Smolarz, Beata Zadrożna-Nowak, Anna Romanowicz, Hanna Int J Mol Sci Review Long noncoding RNAs (lncRNAs) are the largest groups of ribonucleic acids, but, despite the increasing amount of literature data, the least understood. Given the involvement of lncRNA in basic cellular processes, especially in the regulation of transcription, the role of these noncoding molecules seems to be of great importance for the proper functioning of the organism. Studies have shown a relationship between disturbed lncRNA expression and the pathogenesis of many diseases, including cancer. The present article presents a detailed review of the latest reports and data regarding the importance of lncRNA in the development of cancers, including breast carcinoma. MDPI 2021-08-05 /pmc/articles/PMC8395147/ /pubmed/34445129 http://dx.doi.org/10.3390/ijms22168427 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Smolarz, Beata
Zadrożna-Nowak, Anna
Romanowicz, Hanna
The Role of lncRNA in the Development of Tumors, including Breast Cancer
title The Role of lncRNA in the Development of Tumors, including Breast Cancer
title_full The Role of lncRNA in the Development of Tumors, including Breast Cancer
title_fullStr The Role of lncRNA in the Development of Tumors, including Breast Cancer
title_full_unstemmed The Role of lncRNA in the Development of Tumors, including Breast Cancer
title_short The Role of lncRNA in the Development of Tumors, including Breast Cancer
title_sort role of lncrna in the development of tumors, including breast cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395147/
https://www.ncbi.nlm.nih.gov/pubmed/34445129
http://dx.doi.org/10.3390/ijms22168427
work_keys_str_mv AT smolarzbeata theroleoflncrnainthedevelopmentoftumorsincludingbreastcancer
AT zadroznanowakanna theroleoflncrnainthedevelopmentoftumorsincludingbreastcancer
AT romanowiczhanna theroleoflncrnainthedevelopmentoftumorsincludingbreastcancer
AT smolarzbeata roleoflncrnainthedevelopmentoftumorsincludingbreastcancer
AT zadroznanowakanna roleoflncrnainthedevelopmentoftumorsincludingbreastcancer
AT romanowiczhanna roleoflncrnainthedevelopmentoftumorsincludingbreastcancer

Ejemplares similares