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NGS Analysis Confirms Common TP53 and RB1 Mutations, and Suggests MYC Amplification in Ocular Adnexal Sebaceous Carcinomas

Ocular adnexal (OA) sebaceous carcinomas generally demonstrate more aggressive clinical and histopathological phenotypes than extraocular cases, but the molecular drivers implicated in their oncogenesis remain poorly defined. A retrospective review of surgical and ocular pathology archives identifie...

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Detalles Bibliográficos
Autores principales:	Peterson, Cornelia, Moore, Robert, Hicks, Jessica L., Morsberger, Laura A., De Marzo, Angelo M., Zou, Ying, Eberhart, Charles G., Campbell, Ashley A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395148/ https://www.ncbi.nlm.nih.gov/pubmed/34445161 http://dx.doi.org/10.3390/ijms22168454

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