Global Lysine Acetylome Analysis of LPS-Stimulated HepG2 Cells Identified Hyperacetylation of PKM2 as a Metabolic Regulator in Sepsis

Sepsis-induced liver dysfunction (SILD) is a common event and is strongly associated with mortality. Establishing a causative link between protein post-translational modification and diseases is challenging. We studied the relationship among lysine acetylation (Kac), sirtuin (SIRTs), and the factors...

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Detalles Bibliográficos
Autores principales: Na, Ann-Yae, Paudel, Sanjita, Choi, Soyoung, Lee, Jun Hyung, Kim, Min-Sik, Bae, Jong-Sup, Lee, Sangkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395202/
https://www.ncbi.nlm.nih.gov/pubmed/34445236
http://dx.doi.org/10.3390/ijms22168529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395202/
https://www.ncbi.nlm.nih.gov/pubmed/34445236
http://dx.doi.org/10.3390/ijms22168529

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