Spironolactone for adult female acne (SAFA): protocol for a double-blind, placebo-controlled, phase III randomised study of spironolactone as systemic therapy for acne in adult women

INTRODUCTION: Acne is one of the most common inflammatory skin diseases worldwide and can have significant psychosocial impact and cause permanent scarring. Spironolactone, a potassium-sparing diuretic, has antiandrogenic properties, potentially reducing sebum production and hyperkeratinisation in a...

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Detalles Bibliográficos
Autores principales: Renz, Susanne, Chinnery, Fay, Stuart, Beth, Day, Laura, Muller, Ingrid, Soulsby, Irene, Nuttall, Jacqui, Thomas, Karen, Thomas, Kim Suzanne, Sach, Tracey, Stanton, Louise, Ridd, Matthew J, Francis, Nick, Little, Paul, Eminton, Zina, Griffiths, Gareth, Layton, Alison M, Santer, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395279/
https://www.ncbi.nlm.nih.gov/pubmed/34446504
http://dx.doi.org/10.1136/bmjopen-2021-053876

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