Cargando…

NAD(H) Regulates the Permeability Transition Pore in Mitochondria through an External Site

The opening of the permeability transition pore (mPTP) in mitochondria initiates cell death in numerous diseases. The regulation of mPTP by NAD(H) in the mitochondrial matrix is well established; however, the role of extramitochondrial (cytosolic) NAD(H) is still unclear. We studied the effect of ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Kharechkina, Ekaterina, Nikiforova, Anna, Kruglov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395297/
https://www.ncbi.nlm.nih.gov/pubmed/34445270
http://dx.doi.org/10.3390/ijms22168560