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NAD(H) Regulates the Permeability Transition Pore in Mitochondria through an External Site
The opening of the permeability transition pore (mPTP) in mitochondria initiates cell death in numerous diseases. The regulation of mPTP by NAD(H) in the mitochondrial matrix is well established; however, the role of extramitochondrial (cytosolic) NAD(H) is still unclear. We studied the effect of ad...
Autores principales: | Kharechkina, Ekaterina, Nikiforova, Anna, Kruglov, Alexey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395297/ https://www.ncbi.nlm.nih.gov/pubmed/34445270 http://dx.doi.org/10.3390/ijms22168560 |
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