Multitumor Case Series of Germline BRCA1, BRCA2 and CHEK2-Mutated Patients Responding Favorably on Immune Checkpoint Inhibitors

In recent years, immune checkpoint inhibitors (ICPI) have become widely used for multiple solid malignancies. Reliable predictive biomarkers for selection of patients who would benefit most are lacking. Several tumor types with somatic or germline alterations in genes involved in the DNA damage resp...

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Detalles Bibliográficos
Autores principales: Kinget, Lisa, Bechter, Oliver, Punie, Kevin, Debruyne, Philip R., Brems, Hilde, Clement, Paul, Roussel, Eduard, Van Herck, Yannick, Albersen, Maarten, Baldewijns, Marcella, Schöffski, Patrick, Beuselinck, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395488/
https://www.ncbi.nlm.nih.gov/pubmed/34449592
http://dx.doi.org/10.3390/curroncol28050280

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