Cargando…
Synthetic mRNAs; Their Analogue Caps and Contribution to Disease
The structure of synthetic mRNAs as used in vaccination against cancer and infectious diseases contain specifically designed caps followed by sequences of the 5′ untranslated repeats of β-globin gene. The strategy for successful design of synthetic mRNAs by chemically modifying their caps aims to in...
Autores principales: | Kyriakopoulos, Anthony M., McCullough, Peter A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395722/ https://www.ncbi.nlm.nih.gov/pubmed/34449596 http://dx.doi.org/10.3390/diseases9030057 |
Ejemplares similares
-
Discovery of m(7)G-cap in eukaryotic mRNAs
por: FURUICHI, Yasuhiro
Publicado: (2015) -
Sensing intracellular signatures with synthetic mRNAs
por: Ono, Hiroki, et al.
Publicado: (2023) -
Hypermethylated-capped selenoprotein mRNAs in mammals
por: Wurth, Laurence, et al.
Publicado: (2014) -
Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs
por: Seneff, Stephanie, et al.
Publicado: (2022) -
Putting an ‘End’ to HIV mRNAs: capping and polyadenylation as potential therapeutic targets
por: Wilusz, Jeffrey
Publicado: (2013)