Cargando…

Insights on Metabolic Reprogramming and Its Therapeutic Potential in Acute Leukemia

Acute leukemias, classified as acute myeloid leukemia and acute lymphoblastic leukemia, represent the most prevalent hematologic tumors in adolescent and young adults. In recent years, new challenges have emerged in order to improve the clinical effectiveness of therapies already in use and reduce t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Martino, Ludovica, Tosello, Valeria, Peroni, Edoardo, Piovan, Erich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395761/ https://www.ncbi.nlm.nih.gov/pubmed/34445444 http://dx.doi.org/10.3390/ijms22168738

Ejemplares similares

Responsiveness to Hedgehog Pathway Inhibitors in T-Cell Acute Lymphoblastic Leukemia Cells Is Highly Dependent on 5′AMP-Activated Kinase Inactivation
por: Tosello, Valeria, et al.
Publicado: (2021)

miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia
por: Saccomani, Valentina, et al.
Publicado: (2020)

Chemotactic Cues for NOTCH1-Dependent Leukemia
por: Piovan, Erich, et al.
Publicado: (2018)

Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death
por: Tosello, Valeria, et al.
Publicado: (2016)

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia
por: Bordin, Fulvio, et al.
Publicado: (2018)

Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia
por: Bongiovanni, Deborah, et al.
Publicado: (2017)

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia
por: Herranz, Daniel, et al.
Publicado: (2015)

Pathological implications of metabolic reprogramming and its therapeutic potential in medulloblastoma
por: Marabitti, Veronica, et al.
Publicado: (2022)

Targeting Metabolic Reprogramming in Acute Myeloid Leukemia
por: Castro, Isabel, et al.
Publicado: (2019)

Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma
por: Pang, Yuyang, et al.
Publicado: (2023)

Glucose metabolic reprogramming and its therapeutic potential in obesity-associated endometrial cancer
por: Huang, Pengzhu, et al.
Publicado: (2023)

Metabolic Reprogramming in Breast Cancer and Its Therapeutic Implications
por: Gandhi, Nishant, et al.
Publicado: (2019)

The Therapeutic Potential of a Strategy to Prevent Acute Myeloid Leukemia Stem Cell Reprogramming in Older Patients
por: Park, Moon Nyeo
Publicado: (2023)

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment
por: Dyczynski, Matheus, et al.
Publicado: (2018)

Metabolic Reprogramming and Cell Adhesion in Acute Leukemia Adaptation to the CNS Niche
por: Sharma, Nitesh D., et al.
Publicado: (2021)

Targeting chemoresistance and mitochondria-dependent metabolic reprogramming in acute myeloid leukemia
por: Feng, Lili, et al.
Publicado: (2023)

Reprogramming of Cellular Metabolism and Its Therapeutic Applications in Thyroid Cancer
por: Nagayama, Yuji, et al.
Publicado: (2022)

Lipid metabolism reprogramming and its potential targets in cancer
por: Cheng, Chunming, et al.
Publicado: (2018)

Metabolic Reprogramming During Multidrug Resistance in Leukemias
por: Vidal, Raphael Silveira, et al.
Publicado: (2018)

Targeting metabolic reprogramming in chronic lymphocytic leukemia
por: Nie, Yu, et al.
Publicado: (2022)

Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities
por: Kerr, Emma, et al.
Publicado: (2016)

Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy
por: Giacomini, Isabella, et al.
Publicado: (2021)

Therapeutic Potential of Tumor Metabolic Reprogramming in Triple-Negative Breast Cancer
por: Munkácsy, Gyöngyi, et al.
Publicado: (2023)

Metabolic reprogramming in cancer: Mechanisms and therapeutics
por: Nong, Shiqi, et al.
Publicado: (2023)

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia
por: Tosello, Valeria, et al.
Publicado: (2018)

Mitochondrial Uncoupling and the Reprograming of Intermediary Metabolism in Leukemia Cells
por: Vélez, Juliana, et al.
Publicado: (2013)

Corrigendum: Metabolic Reprogramming During Multidrug Resistance in Leukemias
por: Vidal, Raphael Silveira, et al.
Publicado: (2018)

Cancer progression by reprogrammed BCAA metabolism in myeloid leukemia
por: Hattori, Ayuna, et al.
Publicado: (2017)

Insights into Modern Therapeutic Approaches in Pediatric Acute Leukemias
por: Panuciak, Kinga, et al.
Publicado: (2022)

Insights on the Interplay between Cells Metabolism and Signaling: A Therapeutic Perspective in Pediatric Acute Leukemias
por: Anselmi, Laura, et al.
Publicado: (2020)

Metabolic Reprogramming of Non-Hodgkin's B-Cell Lymphomas and Potential Therapeutic Strategies
por: Ricci, Jean-Ehrland, et al.
Publicado: (2018)

Molecular Landscape of Acute Myeloid Leukemia: Prognostic and Therapeutic Implications
por: Marando, Ludovica, et al.
Publicado: (2020)

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages
por: Batista-Gonzalez, Ana, et al.
Publicado: (2020)

Targeting Lipid Metabolic Reprogramming as Anticancer Therapeutics
por: Cha, Ji-Young, et al.
Publicado: (2016)

Therapeutic Drug-Induced Metabolic Reprogramming in Glioblastoma
por: Nguyen, Trang T. T., et al.
Publicado: (2022)

Metabolic reprogramming in cancer: mechanistic insights from Drosophila
por: Lam Wong, Kenneth Kin, et al.
Publicado: (2021)

A Metabolic Reprogramming Amino Acid Polymer as an Immunosurveillance Activator and Leukemia Targeting Drug Carrier for T‐Cell Acute Lymphoblastic Leukemia
por: Li, Changzheng, et al.
Publicado: (2022)

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia
por: Baran, Natalia, et al.
Publicado: (2022)

Energy metabolism pathways in breast cancer progression: The reprogramming, crosstalk, and potential therapeutic targets
por: Zheng, Xuewei, et al.
Publicado: (2022)

Editorial: Advances in neural reprogramming, disease modeling and therapeutic insights
por: Lau, Shong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m4ar2u9i7nb2smd52uj9p6jmq5