poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

Mobile genetic elements threaten genome integrity in all organisms. MUT-2/RDE-3 is a ribonucleotidyltransferase required for transposon silencing and RNA interference (RNAi) in C. elegans(1–4). When tethered to RNAs in heterologous expression systems, RDE-3 can add long stretches of alternating non-...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Aditi, Yan, Jenny, Pagano, Daniel J., Dodson, Anne E., Fei, Yuhan, Gorham, Josh, Seidman, J.G., Wickens, Marvin, Kennedy, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396162/
https://www.ncbi.nlm.nih.gov/pubmed/32499657
http://dx.doi.org/10.1038/s41586-020-2323-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396162/
https://www.ncbi.nlm.nih.gov/pubmed/32499657
http://dx.doi.org/10.1038/s41586-020-2323-8

Ejemplares similares