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poly(UG)-tailed RNAs in Genome Protection and Epigenetic Inheritance

Mobile genetic elements threaten genome integrity in all organisms. MUT-2/RDE-3 is a ribonucleotidyltransferase required for transposon silencing and RNA interference (RNAi) in C. elegans(1–4). When tethered to RNAs in heterologous expression systems, RDE-3 can add long stretches of alternating non-...

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Detalles Bibliográficos
Autores principales:	Shukla, Aditi, Yan, Jenny, Pagano, Daniel J., Dodson, Anne E., Fei, Yuhan, Gorham, Josh, Seidman, J.G., Wickens, Marvin, Kennedy, Scott
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396162/ https://www.ncbi.nlm.nih.gov/pubmed/32499657 http://dx.doi.org/10.1038/s41586-020-2323-8

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