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Aurora B Tension Sensing Mechanisms in the Kinetochore Ensure Accurate Chromosome Segregation

The accurate segregation of chromosomes is essential for the survival of organisms and cells. Mistakes can lead to aneuploidy, tumorigenesis and congenital birth defects. The spindle assembly checkpoint ensures that chromosomes properly align on the spindle, with sister chromatids attached to microt...

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Detalles Bibliográficos
Autores principales: McVey, Shelby L., Cosby, Jenna K., Nannas, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396173/
https://www.ncbi.nlm.nih.gov/pubmed/34445523
http://dx.doi.org/10.3390/ijms22168818