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Aurora B Tension Sensing Mechanisms in the Kinetochore Ensure Accurate Chromosome Segregation
The accurate segregation of chromosomes is essential for the survival of organisms and cells. Mistakes can lead to aneuploidy, tumorigenesis and congenital birth defects. The spindle assembly checkpoint ensures that chromosomes properly align on the spindle, with sister chromatids attached to microt...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396173/ https://www.ncbi.nlm.nih.gov/pubmed/34445523 http://dx.doi.org/10.3390/ijms22168818 |