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Selective Expression of a SNARE-Cleaving Protease in Peripheral Sensory Neurons Attenuates Pain-Related Gene Transcription and Neuropeptide Release

Chronic pain is a leading health and socioeconomic problem and an unmet need exists for long-lasting analgesics. SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are required for neuropeptide release and noxious signal transducer surface trafficking, thus, selective ex...

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Detalles Bibliográficos
Autores principales: Wang, Wanzhi, Kong, Miaomiao, Dou, Yu, Xue, Shanghai, Liu, Yang, Zhang, Yinghao, Chen, Weiwei, Li, Yanqing, Dai, Xiaolong, Meng, Jianghui, Wang, Jiafu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396265/
https://www.ncbi.nlm.nih.gov/pubmed/34445536
http://dx.doi.org/10.3390/ijms22168826