Cargando…
Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models
Mammalian transglutaminases (TGs) catalyze calcium-dependent irreversible posttranslational modifications of proteins and their enzymatic activities contribute to the pathogenesis of several human neurodegenerative diseases. Although different transglutaminases are found in many different tissues, t...
Autores principales: | Schulze-Krebs, Anja, Canneva, Fabio, Stemick, Judith, Plank, Anne-Christine, Harrer, Julia, Bates, Gillian P., Aeschlimann, Daniel, Steffan, Joan S., von Hörsten, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396294/ https://www.ncbi.nlm.nih.gov/pubmed/34445621 http://dx.doi.org/10.3390/ijms22168914 |
Ejemplares similares
-
Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington’s Disease
por: Osmand, Alexander P., et al.
Publicado: (2016) -
Tissue Transglutaminase Does Not Contribute to the Formation of Mutant Huntingtin Aggregates
por: Chun, Wanjoo, et al.
Publicado: (2001) -
Huntingtin Lowering Strategies
por: Marxreiter, Franz, et al.
Publicado: (2020) -
Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAG(n51trunc) Model of Huntington Disease
por: Plank, Anne-Christine, et al.
Publicado: (2018) -
Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington’s Disease Knock-In Mouse Models
por: Franich, Nicholas R., et al.
Publicado: (2018)