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Multivariate Assessment for Bioequivalence Based on the Correlation of Random Effect
BACKGROUND AND OBJECTIVE: Bioequivalence tests are fundamental step in assessing the equivalence in bioavailability between a test and reference product. In practice, two separate linear mixed models (LMMs) with random subject effects, which have an area under the concentration-time curve (AUC) and...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396372/ https://www.ncbi.nlm.nih.gov/pubmed/34465979 http://dx.doi.org/10.2147/DDDT.S318576 |