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Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein

The mucus layer protects airway epithelia from damage by noxious agents. Intriguingly, Bordetella pertussis bacteria provoke massive mucus production by nasopharyngeal epithelia during the initial coryza-like catarrhal stage of human pertussis and the pathogen transmits in mucus-containing aerosol d...

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Detalles Bibliográficos
Autores principales: Malandra, Anna, Rahman, Waheed Ur, Klimova, Nela, Streparola, Gaia, Holubova, Jana, Osickova, Adriana, Bariselli, Simone, Sebo, Peter, Osicka, Radim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396599/
https://www.ncbi.nlm.nih.gov/pubmed/34445770
http://dx.doi.org/10.3390/ijms22169064