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Zebrafish Model as a Screen to Prevent Cyst Inflation in Autosomal Dominant Polycystic Kidney Disease

In autosomal dominant polycystic kidney disease (ADPKD), kidney cyst growth requires the recruitment of CFTR (cystic fibrosis transmembrane conductance regulator), the chloride channel that is defective in cystic fibrosis. We have been studying cyst inflation using the zebrafish Kupffer’s vesicle (K...

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Detalles Bibliográficos
Autores principales: Oliveira, Inês, Jacinto, Raquel, Pestana, Sara, Nolasco, Fernando, Calado, Joaquim, Lopes, Susana Santos, Roxo-Rosa, Mónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396643/
https://www.ncbi.nlm.nih.gov/pubmed/34445719
http://dx.doi.org/10.3390/ijms22169013