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Contrasting Local and Macroscopic Effects of Collagen Hydroxylation

Collagen is heavily hydroxylated. Experiments show that proline hydroxylation is important to triple helix (monomer) stability, fibril assembly, and interaction of fibrils with other molecules. Nevertheless, experiments also show that even without hydroxylation, type I collagen does assemble into it...

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Detalles Bibliográficos
Autores principales: Varma, Sameer, Orgel, Joseph P. R. O., Schieber, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396666/
https://www.ncbi.nlm.nih.gov/pubmed/34445791
http://dx.doi.org/10.3390/ijms22169068

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