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Contrasting Local and Macroscopic Effects of Collagen Hydroxylation
Collagen is heavily hydroxylated. Experiments show that proline hydroxylation is important to triple helix (monomer) stability, fibril assembly, and interaction of fibrils with other molecules. Nevertheless, experiments also show that even without hydroxylation, type I collagen does assemble into it...
Autores principales: | Varma, Sameer, Orgel, Joseph P. R. O., Schieber, Jay D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396666/ https://www.ncbi.nlm.nih.gov/pubmed/34445791 http://dx.doi.org/10.3390/ijms22169068 |
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