Cargando…

A unique GCN5 histone acetyltransferase complex controls erythrocyte invasion and virulence in the malaria parasite Plasmodium falciparum

The histone acetyltransferase GCN5-associated SAGA complex is evolutionarily conserved from yeast to human and functions as a general transcription co-activator in global gene regulation. In this study, we identified a divergent GCN5 complex in Plasmodium falciparum, which contains two plant homeodo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miao, Jun, Wang, Chengqi, Lucky, Amuza Byaruhanga, Liang, Xiaoying, Min, Hui, Adapa, Swamy Rakesh, Jiang, Rays, Kim, Kami, Cui, Liwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396726/ https://www.ncbi.nlm.nih.gov/pubmed/34403450 http://dx.doi.org/10.1371/journal.ppat.1009351

Ejemplares similares

A type II protein arginine methyltransferase regulates merozoite invasion in Plasmodium falciparum
por: Lucky, Amuza Byaruhanga, et al.
Publicado: (2023)

Characterization of the dual role of Plasmodium falciparum DNA methyltransferase in regulating transcription and translation
por: Lucky, Amuza B, et al.
Publicado: (2023)

Plasmodium falciparum GCN5 plays a key role in regulating artemisinin resistance-related stress responses
por: Lucky, Amuza Byaruhanga, et al.
Publicado: (2023)

Punctuated chromatin states regulate Plasmodium falciparum antigenic variation at the intron and 2 kb upstream regions
por: Wang, Chengqi, et al.
Publicado: (2016)

Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum
por: Rawat, Mukul, et al.
Publicado: (2021)

Gcn5 histone acetyltransferase is present in the mitoplasts
por: Montanari, Arianna, et al.
Publicado: (2019)

Plasmodium knowlesi Skeleton-Binding Protein 1 Localizes to the ‘Sinton and Mulligan’ Stipplings in the Cytoplasm of Monkey and Human Erythrocytes
por: Lucky, Amuza Byaruhanga, et al.
Publicado: (2016)

And-1 is required for the stability of histone acetyltransferase Gcn5
por: Li, Yongming, et al.
Publicado: (2011)

Investigation of the Acetylation Mechanism by GCN5 Histone Acetyltransferase
por: Jiang, Junfeng, et al.
Publicado: (2012)

Plasmodium vivax readiness to transmit: implication for malaria eradication
por: Adapa, Swamy Rakesh, et al.
Publicado: (2019)

Influence of Plasmodium falciparum Calcium-Dependent Protein Kinase 5 (PfCDPK5) on the Late Schizont Stage Phosphoproteome
por: Blomqvist, Karin, et al.
Publicado: (2020)

Chemogenomic Profiling of a Plasmodium falciparum Transposon Mutant Library Reveals Shared Effects of Dihydroartemisinin and Bortezomib on Lipid Metabolism and Exported Proteins
por: Pires, Camilla Valente, et al.
Publicado: (2023)

Diversification of the Histone Acetyltransferase GCN5 through Alternative Splicing in Brachypodium distachyon
por: Martel, Alexandre, et al.
Publicado: (2017)

Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5
por: Hatakeyama, Dai, et al.
Publicado: (2018)

The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes
por: Rosaleny, Lorena E, et al.
Publicado: (2007)

Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells
por: Koutsogiannouli, Evangelia A., et al.
Publicado: (2017)

Histone Acetyltransferase CfGcn5-Mediated Autophagy Governs the Pathogenicity of Colletotrichum fructicola
por: Zhang, Shengpei, et al.
Publicado: (2022)

Altered expression of K13 disrupts DNA replication and repair in Plasmodium falciparum
por: Gibbons, Justin, et al.
Publicado: (2018)

Posttranslational regulation of the GCN5 and PCAF acetyltransferases
por: Ononye, Onyekachi E., et al.
Publicado: (2022)

SICA-mediated cytoadhesion of Plasmodium knowlesi-infected red blood cells to human umbilical vein endothelial cells
por: Chuang, Huai, et al.
Publicado: (2022)

The Aspergillus flavus Histone Acetyltransferase AflGcnE Regulates Morphogenesis, Aflatoxin Biosynthesis, and Pathogenicity
por: Lan, Huahui, et al.
Publicado: (2016)

Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines
por: Huang, Boyue, et al.
Publicado: (2020)

Histone Acetyltransferase SlGCN5 Regulates Shoot Meristem and Flower Development in Solanum lycopersicum
por: Hawar, Amangul, et al.
Publicado: (2022)

Functional Characterization of the GNAT Family Histone Acetyltransferase Elp3 and GcnE in Aspergillus fumigatus
por: Choi, Young-Ho, et al.
Publicado: (2023)

Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome
por: Xue-Franzén, Yongtao, et al.
Publicado: (2013)

Histone Acetyltransferase GCN5 Affects Auxin Transport during Root Growth by Modulating Histone Acetylation and Gene Expression of PINs
por: Poulios, Stylianos, et al.
Publicado: (2022)

Plasmodium falciparum Secretome in Erythrocyte and Beyond
por: Soni, Rani, et al.
Publicado: (2016)

Plasmodium falciparum-infected erythrocytes form spontaneous erythrocyte rosettes
Publicado: (1989)

The histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect trichome initiation in Arabidopsis thaliana
por: Hark, Amy T, et al.
Publicado: (2019)

The Histone Acetyltransferase HpGCN5 Involved in the Regulation of Abiotic Stress Responses and Astaxanthin Accumulation in Haematococcus pluvialis
por: Huang, Danqiong, et al.
Publicado: (2022)

Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook
por: Siddiqui, Faiza Amber, et al.
Publicado: (2021)

Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation
por: Wang, Jiachen, et al.
Publicado: (2014)

Characterization of yeast histone H3-specific type B histone acetyltransferases identifies an ADA2-independent Gcn5p activity
por: Sklenar, Amy R, et al.
Publicado: (2004)

Erythrocyte Membrane Makeover by Plasmodium falciparum Gametocytes
por: Neveu, Gaëlle, et al.
Publicado: (2019)

Lyse-Reseal Erythrocytes for Transfection of Plasmodium falciparum
por: Govindarajalu, Gokulapriya, et al.
Publicado: (2019)

Does gene length play a role? — Transient regulation of Gcn5 histone acetyltransferase under stress conditions
por: Xue-Franzén, Yongtao
Publicado: (2014)

Disruption of the histone acetyltransferase GCN5 and the transcriptional coactivator ADA2b affect trichome density in Arabidopsis thaliana
por: Kotak, Jenna, et al.
Publicado: (2019)

The Histone Acetyltransferase GCN5 and the Associated Coactivators ADA2: From Evolution of the SAGA Complex to the Biological Roles in Plants
por: Vlachonasios, Konstantinos, et al.
Publicado: (2021)

Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes
por: Dankwa, Selasi, et al.
Publicado: (2017)

An essential endoplasmic reticulum-resident N-acetyltransferase ortholog in Plasmodium falciparum
por: Polino, Alexander J., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_aavudd27eiussna77jctc4akqk