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Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis

Dosage compensation equalizes X-linked expression between XY males and XX females. In male fruit flies, expression levels of the X-chromosome are increased approximately two-fold to compensate for their single X chromosome. In testis, dosage compensation is thought to cease during meiosis; however,...

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Detalles Bibliográficos
Autores principales: Witt, Evan, Shao, Zhantao, Hu, Chun, Krause, Henry M., Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396764/
https://www.ncbi.nlm.nih.gov/pubmed/34403408
http://dx.doi.org/10.1371/journal.pgen.1009728