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Bistability in fatty-acid oxidation resulting from substrate inhibition

In this study we demonstrated through analytic considerations and numerical studies that the mitochondrial fatty-acid β-oxidation can exhibit bistable-hysteresis behavior. In an experimentally validated computational model we identified a specific region in the parameter space in which two distinct...

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Detalles Bibliográficos
Autores principales: Abegaz, Fentaw, Martines, Anne-Claire M. F., Vieira-Lara, Marcel A., Rios-Morales, Melany, Reijngoud, Dirk-Jan, Wit, Ernst C., Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396765/
https://www.ncbi.nlm.nih.gov/pubmed/34383741
http://dx.doi.org/10.1371/journal.pcbi.1009259