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Bistability in fatty-acid oxidation resulting from substrate inhibition
In this study we demonstrated through analytic considerations and numerical studies that the mitochondrial fatty-acid β-oxidation can exhibit bistable-hysteresis behavior. In an experimentally validated computational model we identified a specific region in the parameter space in which two distinct...
Autores principales: | Abegaz, Fentaw, Martines, Anne-Claire M. F., Vieira-Lara, Marcel A., Rios-Morales, Melany, Reijngoud, Dirk-Jan, Wit, Ernst C., Bakker, Barbara M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396765/ https://www.ncbi.nlm.nih.gov/pubmed/34383741 http://dx.doi.org/10.1371/journal.pcbi.1009259 |
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