Cargando…
3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up
Wide resection is currently considered the mainstay treatment for primary bone tumors. When the tumor is located in anatomically complex segments, 3D-Printed Titanium Custom-Made Prostheses (3DPTCMP) are possible reconstructive solutions. The aim of the present paper is to analyze indications, resul...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397106/ https://www.ncbi.nlm.nih.gov/pubmed/34441834 http://dx.doi.org/10.3390/jcm10163539 |
_version_ | 1783744539837595648 |
---|---|
author | Zoccali, Carmine Baldi, Jacopo Attala, Dario Scotto di Uccio, Alessandra Cannavò, Luca Scotto, Gennaro Luzzati, Alessandro |
author_facet | Zoccali, Carmine Baldi, Jacopo Attala, Dario Scotto di Uccio, Alessandra Cannavò, Luca Scotto, Gennaro Luzzati, Alessandro |
author_sort | Zoccali, Carmine |
collection | PubMed |
description | Wide resection is currently considered the mainstay treatment for primary bone tumors. When the tumor is located in anatomically complex segments, 3D-Printed Titanium Custom-Made Prostheses (3DPTCMP) are possible reconstructive solutions. The aim of the present paper is to analyze indications, results and complications of a series of 14 patients who underwent pelvis reconstruction with 3DPTCMP after tumor removal from January 2015 to December 2019. Chondrosarcoma was the main histology; indications were tumors located in the acetabular area without enough residual bone to support a cup with an iliac stem, and tumors located near the sacrum-iliac joint. The margins were wide in 12 cases, and marginal and intralesional in one case each. In three cases, resection also included the sacrum-iliac joint, so a spine stabilization was performed and linked to the pelvic prosthesis; The average MSTS score was 46.3%; the 5-year local recurrence-free survival was 85.7%. Wound dehiscences were the main complication, resolved with multiple debridements; nevertheless, prosthesis removal was necessary in one case. Currently, the 3DPTCMP is an effective resource for reconstruction after resection of tumors located in the pelvis. Further studies are necessary to value long-term results; more strategies are necessary to try to reduce the infection rate and improve osteointegration. |
format | Online Article Text |
id | pubmed-8397106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83971062021-08-28 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up Zoccali, Carmine Baldi, Jacopo Attala, Dario Scotto di Uccio, Alessandra Cannavò, Luca Scotto, Gennaro Luzzati, Alessandro J Clin Med Article Wide resection is currently considered the mainstay treatment for primary bone tumors. When the tumor is located in anatomically complex segments, 3D-Printed Titanium Custom-Made Prostheses (3DPTCMP) are possible reconstructive solutions. The aim of the present paper is to analyze indications, results and complications of a series of 14 patients who underwent pelvis reconstruction with 3DPTCMP after tumor removal from January 2015 to December 2019. Chondrosarcoma was the main histology; indications were tumors located in the acetabular area without enough residual bone to support a cup with an iliac stem, and tumors located near the sacrum-iliac joint. The margins were wide in 12 cases, and marginal and intralesional in one case each. In three cases, resection also included the sacrum-iliac joint, so a spine stabilization was performed and linked to the pelvic prosthesis; The average MSTS score was 46.3%; the 5-year local recurrence-free survival was 85.7%. Wound dehiscences were the main complication, resolved with multiple debridements; nevertheless, prosthesis removal was necessary in one case. Currently, the 3DPTCMP is an effective resource for reconstruction after resection of tumors located in the pelvis. Further studies are necessary to value long-term results; more strategies are necessary to try to reduce the infection rate and improve osteointegration. MDPI 2021-08-12 /pmc/articles/PMC8397106/ /pubmed/34441834 http://dx.doi.org/10.3390/jcm10163539 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zoccali, Carmine Baldi, Jacopo Attala, Dario Scotto di Uccio, Alessandra Cannavò, Luca Scotto, Gennaro Luzzati, Alessandro 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title | 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title_full | 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title_fullStr | 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title_full_unstemmed | 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title_short | 3D-Printed Titanium Custom-Made Prostheses in Reconstruction after Pelvic Tumor Resection: Indications and Results in a Series of 14 Patients at 42 Months of Average Follow-Up |
title_sort | 3d-printed titanium custom-made prostheses in reconstruction after pelvic tumor resection: indications and results in a series of 14 patients at 42 months of average follow-up |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397106/ https://www.ncbi.nlm.nih.gov/pubmed/34441834 http://dx.doi.org/10.3390/jcm10163539 |
work_keys_str_mv | AT zoccalicarmine 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT baldijacopo 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT attaladario 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT scottodiuccioalessandra 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT cannavoluca 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT scottogennaro 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup AT luzzatialessandro 3dprintedtitaniumcustommadeprosthesesinreconstructionafterpelvictumorresectionindicationsandresultsinaseriesof14patientsat42monthsofaveragefollowup |