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No ordinary proteins: Adsorption and molecular orientation of monoclonal antibodies

The interaction of monoclonal antibodies (mAbs) with air/water interfaces plays a crucial role in their overall stability in solution. We aim to understand this behavior using pendant bubble measurements to track the dynamic tension reduction and x-ray reflectivity to obtain the electron density pro...

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Detalles Bibliográficos
Autores principales: Kanthe, Ankit, Ilott, Andrew, Krause, Mary, Zheng, Songyan, Li, Jinjiang, Bu, Wei, Bera, Mrinal K., Lin, Binhua, Maldarelli, Charles, Tu, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397265/
https://www.ncbi.nlm.nih.gov/pubmed/34452912
http://dx.doi.org/10.1126/sciadv.abg2873