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From Preassociation to Chelation: A Survey of Cisplatin Interaction with Methionine at Molecular Level by IR Ion Spectroscopy and Computations

[Image: see text] Methionine (Met) plays an important role in the metabolism of cisplatin anticancer drug. Yet, methionine platination in aqueous solution presents a highly complex pattern of interconnected paths and intermediates. This study reports on the reaction of methionine with the active aqu...

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Detalles Bibliográficos
Autores principales: Paciotti, Roberto, Corinti, Davide, Maitre, Philippe, Coletti, Cecilia, Re, Nazzareno, Chiavarino, Barbara, Crestoni, Maria Elisa, Fornarini, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397306/
https://www.ncbi.nlm.nih.gov/pubmed/34236851
http://dx.doi.org/10.1021/jasms.1c00152