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From Preassociation to Chelation: A Survey of Cisplatin Interaction with Methionine at Molecular Level by IR Ion Spectroscopy and Computations
[Image: see text] Methionine (Met) plays an important role in the metabolism of cisplatin anticancer drug. Yet, methionine platination in aqueous solution presents a highly complex pattern of interconnected paths and intermediates. This study reports on the reaction of methionine with the active aqu...
Autores principales: | Paciotti, Roberto, Corinti, Davide, Maitre, Philippe, Coletti, Cecilia, Re, Nazzareno, Chiavarino, Barbara, Crestoni, Maria Elisa, Fornarini, Simonetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397306/ https://www.ncbi.nlm.nih.gov/pubmed/34236851 http://dx.doi.org/10.1021/jasms.1c00152 |
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