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Slow Escape from a Helical Misfolded State of the Pore-Forming Toxin Cytolysin A
[Image: see text] The pore-forming toxin cytolysin A (ClyA) is expressed as a large α-helical monomer that, upon interaction with membranes, undergoes a major conformational rearrangement into the protomer conformation, which then assembles into a cytolytic pore. Here, we investigate the folding kin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397351/ https://www.ncbi.nlm.nih.gov/pubmed/34467360 http://dx.doi.org/10.1021/jacsau.1c00175 |