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Slow Escape from a Helical Misfolded State of the Pore-Forming Toxin Cytolysin A

[Image: see text] The pore-forming toxin cytolysin A (ClyA) is expressed as a large α-helical monomer that, upon interaction with membranes, undergoes a major conformational rearrangement into the protomer conformation, which then assembles into a cytolytic pore. Here, we investigate the folding kin...

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Detalles Bibliográficos
Autores principales:	Dingfelder, Fabian, Macocco, Iuri, Benke, Stephan, Nettels, Daniel, Faccioli, Pietro, Schuler, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397351/ https://www.ncbi.nlm.nih.gov/pubmed/34467360 http://dx.doi.org/10.1021/jacsau.1c00175

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