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High-Pressure Dielectric Studies—a Way to Experimentally Determine the Solubility of a Drug in the Polymer Matrix at Low Temperatures

[Image: see text] In this work, we employed broad-band dielectric spectroscopy to determine the solubility limits of nimesulide in the Kollidon VA64 matrix at ambient and elevated pressure conditions. Our studies confirmed that the solubility of the drug in the polymer matrix decreases with increasi...

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Detalles Bibliográficos
Autores principales:	Chmiel, Krzysztof, Knapik-Kowalczuk, Justyna, Kamińska, Ewa, Tajber, Lidia, Paluch, Marian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397395/ https://www.ncbi.nlm.nih.gov/pubmed/34250800 http://dx.doi.org/10.1021/acs.molpharmaceut.1c00264

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