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Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice

The cleavage of osteopontin (OPN) by thrombin results in an N-terminal fragment (OPN-N), which exposes a cryptic integrin-binding motif that promotes the adherence of cells, and plays a proinflammatory role. However, the effect of OPN-N on abdominal aortic aneurysm (AAA) remains unknown. The aim of...

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Detalles Bibliográficos
Autores principales:	Liu, Hongyang, Zhang, Ying, Song, Wei, Sun, Yancui, Jiang, Yinong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397420/ https://www.ncbi.nlm.nih.gov/pubmed/34458254 http://dx.doi.org/10.3389/fcell.2021.681790

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