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Manipulating the NKG2D Receptor-Ligand Axis Using CRISPR: Novel Technologies for Improved Host Immunity

The activating immune receptor natural killer group member D (NKG2D) and its cognate ligands represent a fundamental surveillance system of cellular distress, damage or transformation. Signaling through the NKG2D receptor-ligand axis is critical for early detection of viral infection or oncogenic tr...

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Detalles Bibliográficos
Autores principales: Alves, Eric, McLeish, Emily, Blancafort, Pilar, Coudert, Jerome D., Gaudieri, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397441/
https://www.ncbi.nlm.nih.gov/pubmed/34456921
http://dx.doi.org/10.3389/fimmu.2021.712722