Class I PI3K Provide Lipid Substrate in T Cell Autophagy Through Linked Activity of Inositol Phosphatases

Autophagy, a highly conserved intracellular process, has been identified as a novel mechanism regulating T lymphocyte homeostasis. Herein, we demonstrate that both starvation- and T cell receptor-mediated autophagy induction requires class I phosphatidylinositol-3 kinases to produce PI(3)P. In contr...

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Detalles Bibliográficos
Autores principales: McLeod, Ian X., Saxena, Ruchi, Carico, Zachary, He, You-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397451/
https://www.ncbi.nlm.nih.gov/pubmed/34458267
http://dx.doi.org/10.3389/fcell.2021.709398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8397451/
https://www.ncbi.nlm.nih.gov/pubmed/34458267
http://dx.doi.org/10.3389/fcell.2021.709398

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